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. 2021 Jul 12;11(7):1807. doi: 10.3390/nano11071807

Figure 6.

Figure 6

Secretion of pro-inflammatory cytokines as a marker of intracellular stress. The in vitro systems underwent a 24 h exposure, either untreated or following introduction of 5 µg/mL AgNPs, after which the media was evaluated for secreted levels of the pro-inflammatory cytokines of (A) IL-1β, (B), IL-6, (C) IL-8, and (D) TNF-α. * and † denote statistical significance from static, untreated A549 cells and between A549/U937 static and dynamic at the same AgNP concentration, respectively, n = 3, p < 0.05.