Table 2.
Adjusted means and 95% confidence intervals of metabolic syndrome-related parameters according to immunity status.
| L-WBC+L-CRP (n = 25,604) |
H-WBC+L-CRP (n = 13,880) |
L-WBC+H-CRP (n = 464) |
H-WBC+H-CRP (n = 820) |
|
|---|---|---|---|---|
| WBC (109/L) | 4.83 (4.82–4.85) c | 7.18 (7.17–7.20) b | 4.84 (4.54–4.93) c | 7.97 (7.91–8.04) a***# |
| Serum CRP (mg/dL) | 0.08 (0.08–0.08) d |
0.11 (0.10-0.11) c |
1.2 (1.179–1.23) b |
1.39 (1.37–1.41) a***# |
| BMI (kg/m2) | 23.6 (23.6–23.6) c | 24.3 (24.2–24.3) b | 24.3 (24.1–24.6) a | 24.9 (24.7–25.1) a***# |
| Waist circumferences (cm) | 80.2 (80.2–80.3) b |
80.7 (80.7–80.8) a |
80.5 (80.0–80.9) ab |
80.9 (80.6–81.2) a***# |
| Serum glucose (mg/dL) | 94.2 | 96.9 | 97.4 | 100.2 |
| (93.9–94.4) c | (96.6–97.3) b | (95.6–99.2) b | (98.9–102) a***# | |
| Blood HbA1c (%) | 5.64 (5.63–5.65) c |
5.82 (5.81–5.83) b |
5.77 (5.70–5.83) b |
5.96 (5.92–6.01) a***# |
| Serum total cholesterol (mg/dL) | 197 (197–198) b | 200 (199–200) a | 193 (190–196) b | 196 (194–199) b***# |
| Serum HDL (mg/dL) | 55.2 (55.0–55.3) a |
53.5 (53.3–53.8) b |
53.1 (52.0–54.3) b |
52 (51.1–52.8) c***# |
| Serum LDL (mg/dL) | 118 (118–119) | 118 (117–119) | 116 (113–119) | 119 (116–122) |
| Serum TG (mg/dL) | 119 (118–120) b | 140 (138–141) a | 118 (111–126) b | 126 (119–131) b***# |
| SBP (mmHg) | 122 (122–122) b | 124 (123–124) a | 122 (121–123) ab | 123 (122–124) a** |
| DBP (mmHg) | 75.1 (75.0–75.2) b | 75.8 (75.1–76.4) ab | 75.3 (74.5–76.2) ab | 75.9 (75.7–76.1) a** |
| Serum AST | 23.4 | 23.9 | 24.7 | 30.7 |
| (IU/L) | (23.1–23.7) b | (23.4–23.9) b | (22.3–27.0) b | (28.9–32.4) a***# |
| Serum ALT | 21.4 | 22.8 | 23.1 | 27.8 |
| (IU/L) | (21.1–21.8) b | (22.5–23.2) b | (21.0–25.2) b | (26.3–29.4) a***# |
Immunity was categorized into four groups: L-WBC+L-CRP, H-WBC+L-CRP, L-WBC+H-CRP, and H-WBC+H-CRP. Their cutoffs were <6.2 × 109/L for white blood cell counts (L-WBC) and <0.5 mg/dL serum CRP concentrations (L-CRP) for low levels. H-WBC and H-CRP represented their high levels. SBP, systolic blood pressure; DBP, diastolic blood pressure; AST, aspartate aminotransferase; ALT, alanine aminotransferase; TG, triglyceride. Adjusted for covariates, including age, gender, body mass index, daily energy intake, income, education, the incidence of arthritis, allergy, asthmas, gastritis, gastric ulcer, gallstone, bronchitis, urethritis, physical activity, alcohol intake, and smoking status. ** Significant difference by the immunity groups in one-way ANCOVA test at p < 0.01 and *** at p < 0.0001. # Significant difference by the immunity groups in one-way ANCOVA test with Bonferroni correction at p < 0.002. a,b,c,d Different letters indicated significant differences among the groups in the Tukey test at p < 0.05.