Table 3.

The role of proteins from the LTTR family in the virulence of Salmonella.

LTTR System	Function	Reference
SpvR	enhancing bacterial virulence by inhibiting autophagy; inducing the spv operon expression in the intracellular environment of host cells	[160,161]
LeuO	forming tetramer residues involved in oligomerization, DNA binding, transcriptional regulation	[158,162]
LoiA	encoded by SPI-14; essential for the Salmonella invasion of intestinal epithetical cells	[40,163]
STM0030	regulating genes essential for Salmonella intracellular replication and virulence	[40]
CysB	activator of the Cys regulon under the sulfur limitation	[164,165]
LtrR	indirect regulation of the porin synthesis; bacterial transformation and bile resistance	[166]
Hrg	protection against oxidative stress; bacterial growth and survival within macrophages	[167]