Table 2.
The distance that mice swam for the platform search.
| Acquisition | Learning | Probe | ||||
|---|---|---|---|---|---|---|
| Start SW | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 6 |
| N; E; SE; NW | SE; N; NW; E | NW; SE; E; N | E; NW; N; SE | N; SE; E; NW | NW | |
| Control | 2611 ± 514 | 1852 ± 306 | 1511 ± 266 | 1956 ± 313 | 1265 ± 232 | 1401 ± 410 |
| DMF | 2512 ± 230 | 2018 ± 151 | 2130 ± 201 | 2035 ± 187 | 1887 ± 222 | 2897 ± 359 |
| MB | 2573 ± 266 | 1960 ± 257 | 2174 ± 276 | 1134 ± 192 | 1654 ± 295 | 1682 ± 464 |
| RSV | 1896 ± 238 | 1894 ± 220 | 1724 ± 236 | 1461 ± 195 | 1544 ± 223 | 1376 ± 385 |
| Reversal | Learning | Probe | ||||
| Start NE | Day 7 | Day 8 | Day 9 | Day 10 | Day 11 | Day 12 |
| S; W; NW; SE | NW; S; SE; W | SE; NW; W; S | W; SE; S; NW | S; NW; W; SE | SE | |
| Control | 2774 ± 423 | 2306 ± 398 | 2726 ± 420 | 2212 ± 213 | 2064 ± 498 | 1324 ± 443 |
| DMF | 1228 ± 184 ** | 1491 ± 195 | 996 ± 174 *** | 1122 ± 153 ** | 1142 ± 154 * | 1062 ± 401 |
| MB | 1113 ± 217 ** | 920 ± 188 ** | 1335 ± 266* | 1195 ± 179 * | 682 ± 116 *** | 1838 ± 334 |
| RSV | 1430 ± 195 * | 1107 ± 165 * | 1229 ± 201 ** | 1160 ± 163 ** | 1076 ± 168 * | 1691 ± 338 |
The results expressed as means ± SEM. Control n = 8, DMF = 9, MB = 6, RSV = 8. * p < 0.05, ** p < 0.01, *** p < 0.001, comparison of the control group and treated groups using Tukey’s post-hoc test.