Table 4.
The association between each instrumental variable and confounding factors.
| Instrumental Variable | Confounding Factors (Beta (Standard Error), p-Value) | |||
|---|---|---|---|---|
| Smoking | Alcohol Consumption | Dietary Habits (RFS) | BMI | |
| rs12567136 | 0.22(0.32),0.50 | −0.11(0.29),0.70 | 1.21(1.03),0.24 | −0.05(0.38),0.89 |
| rs1801133 | 0.02(0.11),0.85 | 0.01(0.08),0.91 | −0.54(0.28),0.05 | −0.05(0.11),0.62 |
| rs2336377 | −0.06(0.12),0.60 | 0.03(0.09),0.72 | 0.10(0.31),0.75 | 0.11(0.12),0.35 |
| rs1624230 | −0.15(0.13),0.25 | 0.12(0.10),0.22 | 0.12(0.34),0.73 | −0.19(0.13),0.15 |
| rs1836883 | 0.16(0.11),0.13 | 0.03(0.08),0.73 | −0.40(0.27),0.15 | −0.08(0.10),0.44 |
RFS, recommended food score; BMI, body mass index; Smoking: current smoker vs non-, ex-smoker; Drinking: current drinker vs non-, ex-drinker. Analyses were adjusted for age, sex, and area. Genetic model is additive.