Table 2.
Effects on serum biochemistry in normal and diabetic Wistar rats.
| Biochemical Parameters | Abbreviation | Unit | Group-I | Group-II | Group-III | Group-IV | One Way ANOVA p Value |
|---|---|---|---|---|---|---|---|
| Glycated hemoglobin | HbA1c | % | 0.41 ± 0.11 | 0.95 ± 0.14 *,a | 0.82 ± 0.09 | 0.53 ± 0.08 | 0.0068 |
| Blood glucose level | BGL | mg/dL | 178 ± 42 | 444 ± 37 ***,a | 343 ± 28 *,a | 280 ± 49 *,b | 0.0012 |
| Alkaline Phosphatase | ALP | U/L | 206 ± 47 | 1183 ± 388 *,a | 813 ± 157 | 652 ± 169 | 0.0462 |
| Alanine aminotransferase | ALT | U/L | 43.35 ± 4.46 | 66.62 ± 11.41 | 47.50 ± 6.10 | 55.16 ± 7.28 | 0.1912 |
| Aspartate Aminotransferase | AST | U/L | 78.03 ± 10 | 108.99 ± 13 | 83.57 ± 11 | 89.50 ± 8 | 0.2204 |
| Blood urea nitrogen | BUN | µm/L | 66.31 ± 22 | 183.30 ± 51 | 129.85 ± 15 | 131.67 ± 27 | 0.1114 |
| Creatinine | Cr | µm/L | 64.71 ± 22 | 85.97 ± 6 | 54.58 ± 28 | 61.71 ± 15 | 0.7018 |
Data were expressed as Mean ± S.E. (n = 6). Statistical analysis was conducted by one-way ANOVA followed by Tukey post hoc test. The significances were considered as follow (*) p < 0.05 and (***) p < 0.001. Group-I was compared to diabetic groups a, while Group-II was compared to Group-III and Group-IV b.