Table 3.
Quantitative analysis of femur histomorphometry (cortical bone) in normal and diabetic Wistar rats.
| Histomorphometry Parameters | Abbreviation | Unit | Group-I | Group-II | Group-III | Group-IV | One Way ANOVA p Value |
|---|---|---|---|---|---|---|---|
| Osteoclast surface/bone surface | Oc.S/BS | % | 1.9 ± 0.09 | 3.2 ± 0.4 **,a | 2.8 ± 0.3 | 2.1 ± 0.1 *,b | 0.0065 |
| Porosity area/cortical bone area | Po.Ar/Ct.Ar | % | 2.1 ± 0.5 | 4.2 ± 0.4 *,a | 3.4 ± 0.4 | 2.6 ± 0.4 | 0.0126 |
| Osteoid volume/cortical bone area | OV/Ct.Ar | % | 1.4 ± 0.3 | 3.6 ± 0.5 **,a | 2.9 ± 0.55 | 2 ± 0.3 | 0.0084 |
| Mineralizing surface/osteoid surface | MS/BS | % | 57.1 ± 6 | 18.9 ± 4 ***,a | 28.6 ± 5 **,a | 38.4 ± 6 | 0.0004 |
| Fibrosis tissue volume/cortical bone area | Fb.V/Ct.Ar | % | 0.02 ± 0.009 | 0.2 ± 0.04 ***,a | 0.1 ± 0.03 | 0.08 ± 0.02 *,b | 0.0015 |
Data were expressed as Mean ± S.E. (n = 6). Statistical analysis was conducted by one-way ANOVA followed by Tukey post hoc test. The significances were considered as follow (*) p < 0.05, (**) p < 0.01 and (***) p < 0.001. Group-I was compared to diabetic groups a, while Group-II was compared to Group-III and Group-IV b.