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. 2021 Jun 22;14(7):601. doi: 10.3390/ph14070601

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) Stability of the tosylate precursor OTsE-PE2I in the DMSO or MeCN solution at 120 °C added to the dried QMA eluate eluted by Bu₄NH₂PO₄ (K₂CO₃/K₂₂₂ in DMSO added for comparison). (B) Stability of the reference FE-PE2I in the DMSO or MeCN solution at 120 °C added to the dried QMA eluate eluted by Bu₄NH₂PO₄ (K₂CO₃/K₂₂₂ in DMSO added for comparison). (C) Radiochemical conversion for [¹⁸F]FE-PE2I using CO₃²⁻-preconditioned QMA eluted by 20 mM solution of Bu₄NH₂PO₄ in DMSO or MeCN.