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. 2021 Jul 21;9:e11855. doi: 10.7717/peerj.11855

Table 2. Subgroup analysis of body mass index and post-cardiac operation atrial fibrillation.

Items Number of studies RR I2 P
Within subgroup Between subgroup
Result of primary analysis 30 1.09 [1.05, 1.12] 82 <0.001 NA
Effect model Random effect 30 1.04 [1.03, 1.04] 82 <0.001 NA
Fixed effect 30 1.03 [1.03,1.04] 82 <0.001
Age ≥65 11 1.12 [1.05, 1.20] 78 <0.001 0.15
<65 15 1.06 [1.02, 1.12] 78 0.002
Region Northern America 16 1.07 [1.04, 1.10] 84 <0.001 0.25
Europe 7 1.23 [1.04, 1.45] 75 0.01
Asia 2 0.95 [0.71, 1.27] 70 0.53
Oceania 4 1.11[1.06, 1.17] 0 <0.001
NOS scores <7 scores 7 1.03 [1.00, 1.05] 69 0.05 <0.001
≥7 scores 20 1.12 [1.08, 1.16] 64 <0.001
Publication year 1999-2010 10 1.12 [1.06, 1.17] 58 <0.001 0.25
2011-2020 20 1.08[1.04, 1.11] 85 <0.001
AF Diagnosis ECG 26 1.14 [1.09, 1.19] 67 <0.001 0.33
Others 4 1.03 [0.97, 1.09] 81 0.37
Sample size <1000 8 1.20 [0.93, 1.53] 87 0.16 0.37
≥ 1000 22 1.07 [1.04, 1.09] 75 <0.001
Cases Case <100 4 1.48 [1.11, 1.99] 33 0.008 0.06
Case ≥100 26 1.08 [1.05, 1.11] 82 <0.001
Operation type CABG 17 1.07 [1.03, 1.11] 82 0.001 0.23
Valve 2 1.34 [0.81, 2.22] 84 0.25
Mixed 11 1.13 [1.06, 1.19] 78 <0.001
Adjusted factors Age (+) 26 1.09 [1.05, 1.12] 85 <0.001 0.64
Age (-) 4 1.33 [0.95, 1.86] 53 <0.001
Sex (+) 18 1.07 [1.04, 1.11] 86 <0.001 0.28
Sex (-) 12 1.12 [1.04, 1.21] 65 0.003
DM (+) 17 1.09 [1.05, 1.13] 86 <0.001 0.89
DM (-) 13 1.08 [1.02, 1.15] 75 0.01
Hypertension (+) 14 1.07 [1.04, 1.11] 85 <0.001 0.77
Hypertension (-) 16 1.09 [1.02, 1.16] 85 <0.001
COPD (+) 10 1.13 [1.09, 1.17] 33 <0.001 0.14
COPD (-) 20 1.08 [1.05, 1.12] 83 <0.001
CAD (+) 10 1.09 [1.03, 1.15] 86 <0.001 0.60
CAD (-) 17 1.07 [1.03, 1.11] 81 <0.001

Notes.

Abbreviation

NA
not available
ECG
electrocardiograph
CABG
coronary artery bypass grafting
CAD
coronary artery disease
COPD
chronic obstructive pulmonary disease
DM
diabetes mellitus