Table 3.
Formulation, doses and concentration detected for CBD and metabolites in patients.
| Patient ID | Formulation | Dose of CBD (mg/kg/die) | Concentration (ng/mL) | ||||
|---|---|---|---|---|---|---|---|
| 6-α-OH-CBD | 6-β-OH-CBD | 7-OH-CBD | CBD-COOH | CBD | |||
| 1 | GW pharma CBD | 15.25 | 1.15 | 0 | 27.11 | 380.32 | 239.74 |
| 2 | GW pharma CBD | 17.00 | 12.46 | 7.60 | 313.63 | 9707.01 | 279.75 |
| 3 | GW pharma CBD | 9.25 | 4.97 | 2.17 | 298.16 | 10,112.23 | 130.12 |
| 8.15 | 4.02 | 1.33 | 286.99 | 8849.05 | 105.74 | ||
| 4 | GW pharma CBD | 20.00 | 9.04 | 10.14 | 169.39 | 1510.89 | 343.81 |
| 24.45 | 19.13 | 272.55 | 3200.88 | 396.31 | |||
| 5 | GW pharma CBD | 17.20 | 0 | 0.76 | 115.48 | 3030.12 | 80.29 |
| 4.03 | 4.48 | 205.36 | 6616.54 | 170.63 | |||
| 6 | BEDROLITE + BEDICA + pure CBD | 1.20 | 0 | 0 | 14.01 | 300.57 | 13.19 |
| 7 | BEDROLITE | 6.70 | 0 | 0 | 42.34 | 2625.34 | 23.33 |
| 8 | ENECTA CBD Oil | 4.22 | 0 | 0 | 48.73 | 609.89 | 36.02 |
| 9 | BEDROLITE + CBD crystal | 27.00 (1 + 26) | 0 | 0 | 77.52 | 2851.82 | 36.58 |
Abbreviations: 6-α–OH–CBD, 6-α-hydroxycannabidiol; 6-β–OH–CBD, 6-β-hydroxycannabidiol; 7-OH-CBD, 7-hydroxycannabidiol; 7-COOH-CBD, cannabidiol-7-oic acid; CBD, cannabidiol.