Table 1.

Monoamine oxidase inhibitory activities of KBD formula and its component extracts.

Extract	IC50 (µg/mL)		Ki (µg/mL) 3		Si 4
	MAO-A	MAO-B	MAO-A	MAO-B	MAO-A	MAO-B
KBD	342.4 ± 0.849	110.2 ± 0.546	90.223	47.425	1.903	0.526
P. nigrum	396.7 ± 0.058	211.9 ± 0.055	104.531	97.274	1.145	0.873
C. asiatica	127.0 ± 0.065	141.3 ± 0.106	33.465	60.864	0.550	1.819
N. nucifera	141.9 ± 0.065	412.3 ± 0.220	37.391	177.594	0.211	4.750
Clorgyline 1	0.0015 ± 0.00001 µM	2.99 ± 0.162 µM	0.0004	1.288	0.00031	3213.46
Deprenyl 2	687.6 ± 4.879 µM	0.291 ± 0.044 µM	181.200	0.125	1445.58	0.0007

¹ Clorgyline is a selective MAO-A inhibitor. ² Deprenyl is a selective MAO-B inhibitor. ³ Enzyme inhibitor dissociation constant. ⁴ Selectivity index.