Figure 6.

None of the FDA-approved PI drug suppress the activities of the multi-PI resistant HIV-1 _M11PR mutant. (A) yeast colony formation of ZB011 cells. (A-a) Assay controls for yeast colony formation. (A-b) Results of cells treated with pure compounds. (A-c) Results of cells treated with formulated PI drugs. (B) Cellular growth of ZB011 over time. Pictures shown colony formation were taken at 4–5 days after incubation. Cell growth was measured over time as indicated by automated measurement of OD₆₅₀ using a spectrophotometer. Each datum is shown with an average and standard error bar.