Table 1.
Mean fluorescence intensity (Gmean) values following cell incubation with the ADC, trastuzumab or the irrelevant 13R4 antibody as measured by FACS. Values are the mean of fluorescence intensities obtained from two independent experiments (indicated in parentheses).
| 13R4 | TZ | ADC | |
|---|---|---|---|
| MCF-7 |
0.45 (0.6, 0.3) |
13.1 (14.1, 12.2) |
6.7 (7.2, 6.2) |
| T-47D |
0.4 (0.3, 0.5) |
85.0 (65.9, 104.0) |
83.6 (65.1, 102.0) |
| SK-BR-3 |
0.4 (0.3, 0.45) |
88.0 (89.0, 87.0) |
84.6 (86.1, 83.0) |
| SK-OV-3 |
0.5 (0.5, 0.5) |
223.5 (222.0, 225.0) |
180.0 (177.0, 183.0) |