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. 2021 Jun 26;13(7):964. doi: 10.3390/pharmaceutics13070964

Table 2.

Some nanaofibrous materials reported as potential wound dressings.

Nanaofibrous Materials Polymers Bioactive Agents Loaded with Ag Nanoparticles Outcome The Concentration of Ag Nanoparticles References
Nanofibrous mats Polyvinyl Alcohol (PVA) Starch -Sustained release of Ag nanoparticles.
-Wrinkled and porous morphology.
-Antibacterial effect against E. coli and S. aureus.
1 wt% [74]
Chitosan - -Excellent antimicrobial activity against P. aeruginosa and Methicillin-resistant Staphylococcus aureus (MRSA). 0, 0.7, 1.3, 2, 4 wt% [76]
Cellulose acetate - -Good biocompatibility.
Good antimicrobial activity against E. coli and B. subtilis.
0.125, 0.25, 0.37, 0.5 wt% [77]
-Polyethylene oxide
-polycaprolactone
- Good antimicrobial activity. 1–3 wt% [80]
Polycaprolactone and poly vinyl alcohol ascorbyl palmitate -Antimicrobial activity of Ag nanoparticle-loaded mats revealed a 99% reduction against E. coli and S. aureus. 2 wt% [89]
Nanofibrous membranes Polyvinyl alcohol - -Good biocompatibility. 1% w/v [94]
Polyvinyl alcohol - -Potent antibacterial efficacy against E. coli. - [95]
Poly vinyl alcohol, chitosan - -Antibacterial efficacy against S. aureus and E. coli. Promotes the formation of granulation tissue. 1,2, 3, 4, 5 wt% [96]
Gum Arabic, poly caprolactone, poly vinyl alcohol - -Good antibacterial activity against S. aureus, E. coli, P. aeruginosa and C. albicans. 3 wt% [97]
Poly lactic acid - Good antimicrobial efficacy against E. coli P. aeruginosa, S. aureus, M. smegmatis in vitro with bacteria inhibition rate of more than 95.0%. Accelerated wound healing of 99.9% of S. aureus-infected wound. - [98]
Poly (lactide-co-glycolide) - -supports cell attachment, proliferation, and viability of human osteoblast-like MG-63 cells, in vitro. - [99]
Chitosan - -Sustained drug release.
-Accelerated wound healing in vivo.
12, 60 mg [103]
Polyvinyl alcohol, polyethylene - Potent antibacterial activity of 99.9%. 10–100 mL [104]