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. 2021 Jul 15;13(7):1082. doi: 10.3390/pharmaceutics13071082

Figure 2.

Figure 2

Comparison of estrogenic activities of compounds (A–F) and (G) 17β-estradiol (E2) in the absence or presence of ICI 182,780 (ICI), as determined by cell proliferation measured by E-screen assay in MCF-7 cells. * Significant difference between the cells treated with compounds and the untreated cells. # Significant reduction by co-treatment with ICI compared to treatment with compounds alone (n = 3 independent experiments, p < 0.05, Kruskal–Wallis nonparametric test). Data are represented as mean ± SEM.