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. 2021 Jul 1;13(7):1000. doi: 10.3390/pharmaceutics13071000

Table 1.

Physicochemical properties for the five AgNP formulations studied in this work.

Properties AgNP1 AgNP2 AgNP3 AgNP4 AgNP5
Average diameter of metallic cores ØAg (nm) 16.4 ± 8.0 25.4 ± 13.2 19.0 ± 9.3 16.4 ± 8.1 30.6 ± 23.2
TEM size distribution (nm) 5–40 5–60 5–40 5–40 5–80
PVP K-15 a K-17 b K-17 b K-30 c 12.6 KDa
Hydrodynamic diameter Øhydro (nm) 448.7 90.4 43.8 483.2 121.1
Polydispersity index (PDI) 0.813 0.270 0.433 0.555 0.280
Zeta potential ζ (mV) −0.872 −4.56 −5.13 −0.464 −1.46
Surface plasmon resonance (λ) 415 402, 444 402 406, 549 429
TGA analysis
Metallic silver (% w/w) 1.14 ± 0.02 1.32 ± 0.05 1.26 ± 0.03 1.19 ± 0.01 1.31± 0.01
PVP (% w/w) 19.62 ± 0.30 24.49 ± 0.70 24.43 ± 0.20 20.92 ± 0.42 21.67 ± 0.50
H2O (% w/w) 79.24 ± 0.45 74.25 ± 0.60 75.74 ± 0.25 77.89 ± 0.80 77.02 ± 0.40
Morphology Spherical Spherical Mostly Spherical Mostly Spherical Spherical

a K-15: 8000–12,000 kDa; b K-17: 10,000–16,000 kDa; c K-30: 45,000–58,000 kDa.