Table 2.
Toxicity signs and median lethal dose (LD50) of AgNP formulations assessed in this work.
| Formulation | Toxicity Sings 1 | Lethal Dose (mg/Kg) 2 | GHS Category 3 |
|---|---|---|---|
| AgNP1 | Slouching, lethargy, hypothermia, dehydration, over-reactive to tactile stimulation. | 1067 | 4 |
| AgNP2 | Slouching, ruffed hair, vomiting attempt, lethargy, dyspnea, diarrhea, prostration, hypothermia, and seizure. | 1067 | 4 |
| AgNP3 | Lethargy, ruffed hair, slouching, and diarrhea. | 1290 | 4 |
| AgNP4 | Lethargy, slouching, and ruffed hair. | 1806 | 4 |
| AgNP5 | Lethargy, slouching, ruffed hair, and closed eyes. | 1548 | 4 |
1 This column shows all the toxicity signs observed with each formulation. 2 The mean lethal dose (LD50) of silver contained on each AgNPs formulation per kilogram of mouse body weight. 3 Classification based on the Globally Harmonized System (GHS) of Classification and Labeling of Chemicals.