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. 2021 Jun 28;13(7):978. doi: 10.3390/pharmaceutics13070978

Table 2.

Experimental parameters in testing analgesia following treatment with drugs in NVS, nasal water solution (WS), nasal non-vesicular system (NV) and oral preparation (PO) in animal model.

Drug Drug Concentration in Systems (% w/w) Administrated Drug Dose (mg/kg) Testing Time after Treatment (min)
Ketoprofen 3 11 30
Butorphanol Tartrate 0.04 0.15 10
Tramadol HCl 0.9 5 10, 60, 180