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. 2021 Jun 28;13(7):978. doi: 10.3390/pharmaceutics13070978

Table 4.

Pharmacokinetic (pK) parameters for Ketoprofen following nasal administration in the nanovesicular system (KET NVS) as compared to oral preparation (KET PO), (Mean ± SD), (Values obtained using the NCOMP program).

PK Parameters KET NVS KET PO
Tmax (min) 10.0 ± 0.0 30.0 ± 0.0
Cmax (µg/mL) 43.65 ± 8.30 13.68 ± 5.91
AUC0–5h (µg × min/mL) 4130.38 ± 730.58 2642.14 ± 1153.73
F(relative to PO) 1.56