AFM |
atomic force microscopy |
API |
active pharmaceutical ingredient |
CH |
cholesterol |
CMAs |
Critical Material Attributes |
CPPs |
Critical Process Parameters |
CQAs |
Critical Quality Attributes |
DLS |
dynamic light scattering |
DoE |
Design of Experiments |
DPPE-PEG2000 |
1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt) |
DS |
Design Space |
DSC |
differential scanning calorimetry |
DSPE–PEG2000
|
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000] (ammonium salt) |
dTG |
derivative thermogravimetry |
EMA |
European Medicine Agency |
FT-IR |
Fourier-transform infrared spectroscopy |
ICH |
International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use |
LUV |
large unilamellar vesicles |
PBS |
phosphate-buffered saline |
PC |
L-α-phosphatidylcholine |
PdI |
Polydispersity Index |
PE |
phosphatidylethanolamine |
PEG |
polyethylene glycol |
QbD |
Quality by Design |
QTPP |
Quality Target Product Profile |
R&D |
Research and Development |
RA |
Risk Assessment |
Tc
|
gel to liquid-crystalline phase transition temperature |
Tg
|
glass transitions temperature |
TGA |
thermogravimetric analysis |
Tm
|
phase transition temperature |