Table 2.
MIC (µg/mL) values in the presence of [CoCl2(dap)2]Cl (1) and [CoCl2(en)2]Cl (2) passaging results for selected bacterial strains.
| Strains | Compound | Initial MIC (µg/mL) | MIC after 20 Passages (µg/mL) |
|---|---|---|---|
| S. aureus ATCC 6538 | [CoCl2(dap)2]Cl (1) | 375 ± 137 | 667 ± 258 |
| [CoCl2(en)2]Cl (2) | 667 ± 258 | 1333 ± 516 | |
| S. aureus MRSA 6347 | [CoCl2(dap)2]Cl (1) | 458 ± 102 | 1333 ± 516 |
| [CoCl2(en)2]Cl (2) | 667 ± 516 | 2333 ± 817 | |
| P. aeruginosa ATCC 9027 | [CoCl2(dap)2]Cl (1) | 1667 ± 516 | 2333 ± 817 |
| [CoCl2(en)2]Cl (2) | 1500 ± 548 | 2333 ± 817 | |
| P. aeruginosa 12274 | [CoCl2(dap)2]Cl (1) | 667 ± 258 | 1500 ± 548 |
| [CoCl2(en)2]Cl (2) | 1333 ± 516 | 1500 ± 548 |