Table 1.
Process variables and bead materials used in the wet media milling of the fenofibrate suspensions.
| Run No. | Stirrer Speed, ω (rpm) | Bead Loading, c (-) | Bead Material |
|---|---|---|---|
| 1 a | 3000 | 0.35 | CPS |
| 2 a | 3000 | 0.35 | YSZ |
| 3 a | 3000 | 0.50 | CPS |
| 4 a | 3000 | 0.50 | YSZ |
| 5 a | 4000 | 0.35 | CPS |
| 6 a | 4000 | 0.35 | YSZ |
| 7 a | 4000 | 0.50 | CPS |
| 8 a | 4000 | 0.50 | YSZ |
| 9 b | 3500 | 0.425 | CPS |
| 10 b | 3500 | 0.425 | YSZ |
| 11 c | 2550 | 0.298 | CPS |
| 12 c | 2550 | 0.298 | YSZ |
a: Three-factor, two-level, full factorial DOE used in the parameter estimation of the models. b: Center points of the original DOE for the CPS and the YSZ beads. c: Experiments whose variables are outside the domain of the DOE.