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. 2021 Jul 8;13(14):2241. doi: 10.3390/polym13142241

Figure 10.

Figure 10

Diagram of the stages of mucoadhesion. I is the contact stage. During stage II, the polymer chains and the mucosal surface interpenetrate. In stage III, covalent bonds are formed between the entangled polymer chains and the mucosal surface.