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. 2021 Jul 8;13(14):2241. doi: 10.3390/polym13142241

Table 1.

Examples of drug delivery systems manufactured with biopolymer-based polyelectrolyte complexes.

Polyanion Polycation Formulation Drug Reference
Salecan Chitosan Hydrogel Vitamin C Hu et al. [85]
Carboxymethyl xanthan gum N-trimethyl chitosan Hydrogel Ciprofloxacin Hanna and Saad [111]
Alginate
Guar gum
Xanthan gum
Chitosan Tablet Isosorbide nitrate Syed et al. [112]
Xanthan gum Eudragit® E100 Tablet Diclofenac sodium Moin et al. [113]
Kappa, Iota
and Lambda carrageenan
Chitosan Tablet Trimetazidine hydrochloride Li et al. [114]
Eudragit® S100 Chitosan lactate
Chitosan tartrate
Chitosan citrate
Film Tenofovir Cazorla-Luna et al. [36]
Pectin Chitosan Film Theophylline anhydrous Ghaffari et al. [115]
Alginate Chitosan Microparticles Vancomycin Unagolla et al. [116]
Alginate
Eudragit® L100-55
Oligochitosan Microparticles Naproxen Čalija et al. [117]
Pectin Lactoferrin Nanoparticles Curcumin Yan et al. [118]
Poly(maleic acid-alt-ethylene)
Poly(maleic acid-alt-octadecene)
Chitosan Nanoparticles Methotrexate Ciro et al. [119]
Alginate Cationized gelatin Nanoparticles Curcumin Sarika et al. [120]
Pectin Chitosan Nanoparticles Insulin Maciel et al. [121]
Alginate
Xanthan gum
Carbopol®
Chitosan Freeze-dried inserts Fluconazole Darwesh et al. [122]