The cystometric analysis (CMG) of control, ketamine-treated, and norketamine-treated rats. (A) A one-hour period of CMG in each group observed with the recording software, Biopac Student Lab 4.1 (Biopac Systems Inc., Santa Barbara, CA, USA); (B) Statistical analysis of the intercontraction intervals (ICI), threshold pressure, peak pressure, residual urine volume (RV), mean voiding volume (MVV), and bladder compliance. * indicates statistical differences in comparison with the control group, p < 0.05; # indicates statistical differences in comparison with the norketamine group, p < 0.05.