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. 2021 Jul 15;13(7):1371. doi: 10.3390/v13071371

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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OD values representative of antibody reactivity in sera from pre-COVID-19 and confirmed SARS-CoV-2 patients. (A–C) Results of samples tested against RBD. (D–F) Results of samples tested against full-length spike protein. Statistical analysis was performed using Mann–Whitney U tests in GraphPad Prism. The samples represented here were taken >7 days post symptom onset and include 103 pre-COVID-19 and 91 SARS-CoV-2 positive samples. Horizontal lines represent mean values and samples were performed in triplicate. (G–J) Examples of results from longitudinal samples.