Table 1.

Comparison between LAIV and inactivated influenza vaccines.

LAIV	Inactivated Influenza Vaccine	Recombinant HA Quadrivalent Vaccine (e.g., Flublok Quadrivalent)
Induces multifaceted immune responses including humoral (antibody) and T-cell responses.	Inclusive of viral major surface glycoproteins, i.e., hemagglutinin and neuraminidase. Induces mostly antibody responses.	Contains three times more HA than the standard inactivated influenza vaccine. It induces the production of anti-HA antibodies to prevent influenza virus infections.
Licensed for use in recipients aged 2 years and older.	Licensed for use in recipients aged 6 months and older.	Licensed for use in adults aged 18 years old and older.
Administered intranasally (mimicking natural infection).	Administered intramuscularly.	Administered intramuscularly.