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Construction of Ig-adhesins (A). Schematic diagram of CD4/7B2 chimeric adhesin, showing CD4 linked to the H chain of anti-gp41 mAb 7B2 (B). Schematic diagram of linkers successfully used to join CD4 to 7B2 variable regions (C). Microcapillary electrophoresis demonstrating the molecular weights of the heavy and light chains under reducing conditions.
