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. 2021 Jul 14;13(7):487. doi: 10.3390/toxins13070487

Figure 2.

Figure 2

Schematic illustration of three-dimensional RNA folding structures. RNA can form fully paired and non-canonically paired regions, such as hairpins, internal loops, bulges, multi-branch loops and pseudoknots (upper panel). CAG-repeat regions can fold into hairpins in which the opposing strands of the CAG-repeat form Watson–Crick contacts between the G and C positions (indicated as red lines) and wobble pairs at the A–A mismatches (lower panel). In this picture, a terminal loop of seven nucleotides is shown. Created with BioRender.com.