Table 1.
DNA damage repair factors altered by HPV oncoproteins ATM and ATR DNA damage repair factors that are activated or increased in levels through the action of E6 and E7 oncoproteins.
ATM Targets | ATR Targets |
---|---|
ATM, MRE11, RAD50, NBS1, Chk2, BRCA1, RAD51, 53BP1, H2AX, RNF168, Tip60, SMC1 | ATR, ATRIP, Chk1, TopBP1, FANCD2, FANCM, BRCA1, BRCA2, RAD51, p62, H2AX |