Table 5.
Panels A, B, C and D. Estimate of the marginal effect of HCV genotype 3 on lipids using pre-DAA and post-DAA pairs. LDL: low-density lipoprotein cholesterol; and HDL: high-density lipoprotein cholesterol. * Adjusted for time between measurements.
| Biomarker | Adjusted * Difference in Lipid Changes | ||
|---|---|---|---|
| HCV Genotype 3 | Other HCV Genotypes | ||
| Pre-/Post-DAA Variation (95% CI) | Pre-/Post-DAA Variation (95% CI) | Interaction p-Value | |
| Total cholesterol, mg/dL | 37.74 (26.13–49.35) | 21.63 (16.09–27.18) | 0.002 |
| LDL cholesterol, mg/dL | 45.35 (26.38–64.33) | 29.23 (20.87–37.58) | 0.2 |
| HDL cholesterol, mg/dL | 2.82 (−3.29–8.94) | −1.29 (−3.82–1.25) | 0.17 |
| Triglycerides, mg/dL | −4.17 (−25.5–17.16) | 12.65 (−1.20–26.50) | 0.64 |
* adjusted for time between measurements.