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. 2021 Jun 27;13(7):1251. doi: 10.3390/v13071251

Figure 7.

Figure 7

Map of KSHV LANA1 and EBV EBNA1 and amino acid sequence alignment comparing LANA1.CR2 and EBNA1.GAr in the −2 frame (EBNA1ARF). EBNA1 comprises the N terminus, GA-rich central domain, and C-terminal DNA binding domain. Stop codons of the −2 frame are indicated with arrows. Although the EBNA1 GAr (0 frame) has no amino acid similarity to the LANA1 CR, EBNA1ARF has ∼35% similarity to the 0 frame of the LANA1 CR2 domain, and both sequences contain highly acidic QE-rich repeats. From Ref. [5].