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. 2021 Jul 8;9(7):762. doi: 10.3390/vaccines9070762

Table 2.

Schistosome protease inhibitors.

Protease Inhibitor Specie Protease Inhibited Location of Expression References
SmSrpQ Schistosoma mansoni SmCE Cercariae [74]
SmPi56 Schistosoma mansoni NE Adult worms [50,71,73]
ShSPI Schistosoma haematobium Thrombin Surface of adult worms [89,98]
SjB10 Schistosoma japonicum Trypsin, chymotrypsin, pancreatic elastase Cercariae, schistosomula, eggs, adult male worms [97]
SjB6 Schistosoma japonicum Trypsin Eggs [89]
SmKI-1 Schistosoma mansoni Trypsin, chymotrypsin, NE Adults, schistosomula, eggs [67,71]
SjKI-1 Schistosoma japonicum Trypsin, chymotrypsin, NE Eggs, adult worms [71]
SmSPI Schistosoma mansoni Chymotrypsin, PE, NE Head gland of schistosomules, spines of adults [57]