Figure 7.

Design tree of phage lytic proteins targeting bacteria from the Bacilli class. Per position, square brackets contain different domains that can occur at that position. To simplify the designs, CBD homorepeats were condensed to a single occurrence of the domain. To accommodate for architectures of one up to three domains, the subscript “x0-1” has been added to indicate domains that either do not occur or occur once. Domains are color-coded based on their annotation as EAD (blue), CBD (red) or miscellaneous (yellow). The figure also provides the F-score as a measure of how many of the actual architectures fit the rule, as well the support, signifying the total amount of proteins corresponding to this branch. Due to its size, this figure is best viewed digitally. An analogous design tree of phage lytic proteins targeting bacteria from all phyla in PhaLP is available in the supplementary material in text-based format (File S2).