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Example to illustrate lesion segmentation, which include a) the original ROI, b) absolute difference of ROI from low-pass filtered version, c) combination of (a) and (b) which gives the suspicious regions better contrast to the background, d) output of morphological filtering, e) blob with the largest size is selected (a binary version of the lesion), and f) finally segmented lesion area. It is output of mapping (e) to (a).
