Incidence of pantothenic acid availability on wine fermentation. (A) Fermentation parameters during synthetic media fermentation containing variable concentrations of pantothenic acid, with the strains S. cerevisiae ECA5, IR01, IR10 and MTF914. [sugars]res: residual sugars concentration; Rmax: maximal fermentation rate; Tferm: fermentation duration. n.s.: not significant. (B) Boxplots of the production of central carbon metabolites (acetate, α-ketoglutarate, pyruvate, succinate, ethanol and glycerol; g/L) during fermentation by the S. cerevisiae strains ECA5, IR01, IR10 and MTF914 depending on pantothenic acid concentration (10: , 25 , 50 , 100 and 250 µg/L). Biological duplicates were performed for each condition. The bold central line corresponds to the median. The edges of the boxplots are the 1st and 3rd quartiles. The endpoints of the boxplots are calculated using 1.5 times the interquartile range (the distance between the 1st and 3rd quartile).