TABLE 3.

Cutoffs and diagnostic properties of MRPI for the differentiation of patients with PSP from non-PSP participants

Cutoff and statistical values	Automated MRPI
	164 PSP vs 452 non-PSP
Cutoff value	> 13.42
Sensitivity	82.3%
Specificity	93.8%
Accuracy	90.7%
PPV	82.8%
NPV	93.6%
	108 PSP-RS vs 452 non-PSP
Cutoff value	≥ 13.88
Sensitivity	88.9%
Specificity	94.7%
Accuracy	93.6%
PPV	80.0%
NPV	97.3%
	56 PSP-P vs 452 non-PSP
Cutoff value	≥ 12.38
Sensitivity	76.8%
Specificity	87.6%
Accuracy	86.5%
PPV	43.4%
NPV	96.8%

PSP, progressive supranuclear palsy; PSP-P, progressive supranuclear palsy–parkinsonism; PSP-RS, progressive supranuclear palsy–Richardson’s syndrome; non-PSP, Parkinson’s disease patients + multiple system atrophy patients + healthy controls; MRPI, Magnetic Resonance Parkinsonism Index; PPV, positive predictive value; NPV, negative predictive value.