Table 1.
Anthropometric and clinical characteristics of study subjects.
| Count (n = 109) | |
|---|---|
| Sex (male/female) | 37/72 |
| Puberty (prepubertal/pubertal) | 31/78 |
| Prediabetes | 21 (19.3%) |
| Impaired glucose tolerance (IGT) | 7 (8.6%) |
| Metabolic Syndrome | 15 (13.9%) |
| Metabolically unhealthy obesity (MUO) | 81 (74.1%) |
| Type 2 diabetes | 5 (4.6%) |
| Hypertonia | 16 (15.0%) |
| NAFLD | 63 (57.8%) |
| Mean (±SD) | |
|---|---|
| Age | 13.1 ± 2.7 |
| BMI z-score | 2.8 ± 0.5 |
| Waist circumference [cm] | 106.5 ± 15.3 |
| Fasting glucose [mg/dl] | 84.6 ± 9.7 |
| Insulin [µU/ml] | 24.6 (14.9, 33.9)a |
| HOMA-IR | 6.3 ± 5.3 |
| MRI-PDFF [%] | 8.0 (2.0, 19.5)a |
| AST [U/l] | 34.5 ± 18.6 |
| ALT [U/l] | 46.6 ± 47.0 |
| GGT [U/l] | 24.9 ± 18.7 |
| Triglycerides [mg/dl] | 128.2 ± 77.7 |
| Cholesterol [mg/dl] | 168.0 ± 31.2 |
| HDL-C [mg/dl] | 43.4 ± 10.5 |
| LDL [mg/dl] | 99.9 ± 26.3 |
| CK-18 [U/l] | 175.7 ± 200.0 |
| CRP [mg/dl] | 0.6 ± 0.5 |
| IL-6 [pg/ml] | 3.6 ± 2.2 |
| Procalcitonin [ng/ml] | 0.04 ± 0.02 |
| TNFα [pg/ml] | 1.1 ± 0.4 |
| IL-1Ra [pg/ml] | 1,359 ± 2,212 |
aSkewed distribution thus median and interquartile range are presented.