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. 2021 May 13;45(8):1763–1772. doi: 10.1038/s41366-021-00842-1

Table 3.

Correlations of miRNAs with metabolic profile.

HOMA-IRa Triglycerides [mg/dl]a Cholesterol [mg/dl] MRI PDFF [%]a ALT [U/l]a CK-18 [U/l]a
miRNA 192 0.16 0.19* 0.43** 0.38** 0.51** 0.40**
miRNA 122 0.30** 0.24* 0.33** 0.52** 0.65** 0.52**
miRNA 34a 0.16 0.20* 0.24* 0.37** 0.31** 0.33**
miRNA 193b 0.05 0.12 0.21* 0.31** 0.26** 0.26**b,c,d
miRNA 33b 0.11 −0.01 0.28** 0.24* 0.25** 0.17
miRNA 27b −0.03 0.11 0.15 0.1 −0.01 0.11
miRNA 23a −0.13 −0.02 −0.01 −0.04 −0.06 −0.03
miRNA 15a −0.08 0.04 −0.02 −0.16 −0.09 −0.15
miRNA 1290 −0.10 0.06 0.10 0.22* 0.25** 0.18
miRNA 33a −0.09 0.20*b,c,d 0.03 −0.02 0.05 −0.01
miRNA 98 −0.13 −0.01 −0.01 −0.02 −0.01 −0.01
miRNA 144-3p −0.06 −0.07 −0.1 −0.15 0.02 −0.04
miRNA 19 −0.07 −0.08 0.04 −0.11 0.01 −0.14
miRNA 93 −0.11 −0.16 −0.09 −0.14 0.02 0.21*b,c,d
miRNA 197 −0.01 −0.15 −0.13 0.03 0.03 0.01
miRNA 144-5p −0.08 −0.01 −0.06 0.03 −0.09 −0.03

aSpearman rank correlation coefficients and Pearson correlation coefficients for skewed and normally distributed values, respectively. *p < 0.05; **p < 0.01

p > 0.05 if adjusted for bage, csex, dpubertal stage.

Bold values indicate statistical significance.