Skip to main content
. 2021 May 17;45(8):1773–1781. doi: 10.1038/s41366-021-00843-0

Fig. 1. Male mice fed high fat diet have increased body mass and adipose tissue depot mass.

Fig. 1

A Body mass (BM) increase from 6 to 18 weeks of age in male and female mice. Arrow indicates high fat diet (HFD) feeding at 8 weeks of age. # indicates the timepoint when male HFD mice body weight is significantly greater than all other groups (P < 0.05). ┼ indicates when female HFD mice are significantly different than all other groups (P < 0.05). There is a significant effect of time (F (4.4, 161.4) = 302, P < 0.0001), group (F(3.0, 38) = 69.5, P < 0.0001) and interaction between time and group (F (36, 440) = 22.2, P < 0.0001) on the percent increase in body mass. Percentage of body mass comprised of B iBAT, C iWAT and D eWAT of male and female mice fed either standard diet (STD) or HFD for 10 weeks. Data are presented as mean ± SEM, 8-weeks-old males (n = 10), 8-week-old females (n = 9), Male STD (n = 10), Female STD (n = 9), Male HFD (n = 10), Female HFD (n = 10). *P < 0.05, **P < 0.01, ***P < 0.0001. “A” for 8-week-old males compared to Male STD; B 8-week-old females compared to Female STD; C 8-week-old males compared to Male HFD; D 8-week-old females compared female HFD.