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. 2021 Jun 3;45(8):1687–1695. doi: 10.1038/s41366-021-00831-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Total population includes all patients from LIGHT who were on a DPP-4i or GLP-1RA at baseline and received study treatment. Week 52 completers are those in the total population who remained on study therapy at week 52. Week 16 responders are those in the total population who experienced a weight loss of at least 5% at week 16.