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. 2021 May 4;45(8):1656–1667. doi: 10.1038/s41366-021-00823-4

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© The Author(s), under exclusive licence to Springer Nature Limited 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — A Representative pictures of CD206-deficient (CD206^−/−) mice in the ND, ND + PLA2, HFD, and HFD + PLA2 groups after 15 weeks. B Comparisons of body weight (black) and weekly food intake (blue) in the ND, ND + PLA2, HFD. C Representative pictures of epididymal white adipose tissue (eWAT) and inguinal white adipose tissue (iWAT). D eWAT and iWAT weights of ND, ND + PLA2, HFD, and HFD + PLA2 mice after 15 weeks. E M1- and M2-differentiated CD206^−/− mouse bone marrow-derived macrophages were treated with bvPLA2, and their respective marker gene expressions were evaluated by quantitative real-time PCR. All data is represented as the mean ± SEMs; ***P < 0.0001 versus the ND group; ^###P < 0.0001 versus the HFD group; n = 4 (color figure online).