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. 2021 Jun 5;147(9):2555–2567. doi: 10.1007/s00432-021-03673-9

Table 2.

Expression of estrogen-related receptors (ERRs) in ovarian cancer

a) Rate of expression of the indicated receptors. Shown are the numbers of positive samples in relation to the total numbers of ovarian cancer cases (n = 208) or of the subgroups analyzed and the corresponding percent value (in brackets)
ERRα ERRβ ERRγ
All All 191/208 (91.8%) 171/208 (82.2%) 201/208 (96.6%)
G2 52/53 (98.1%) 35/53 (66.0%) 52/53 (98.1%)
G3 114/122 (93.4%) 115/122 (94.2%) 119/122 (97.5%)
FIGO I + II 30/30 (100%) 21/30 (70.0%) 27/30 (90.0%)
FIGO III + IV 107/115 (93.0%) 103/115 (89.6%) 115/115 (100%)
Serous Serous 128/135 (94.8%) 117/135 (86.7%) 132/135 (97.8%)
G2 23/23 (100%) 16/23 (69.6%) 23/23 (100%)
G3 90/97 (92.7%) 86/97 (88.7%) 95/97 (97.9%)
FIGO I + II 16/16 (100%) 13/16 (81.2%) 16/16 (100%)
FIGO III + IV 77/84 (91.7%) 72/84 (85.7%) 82/84 (97.6%)
(b) Mean receptor expression levels in all ovarian cancer specimens and in the serous subgroup. A non-parametric Kruskal–Wallis rank-sum test was used for testing differences in receptor expression of the indicated ERRs among the groups. P values < 0.05 were considered statistically significant (indicated using bold font)
ERRα ERRβ ERRγ
Mean p value Mean p value Mean p value
All G2 1.552 0.699 0.923 0.428 2.230 0.987
G3 1.611 1.056 2.314
FIGO I + II 1.461 0.438 0.846 0.101 1.884 0.004
FIGO III + IV 1.580 1.035 2.277
Serous G2 1.606 0.776 0.909 0.549 2.347 0.284
G3 1.562 0.987 2.183
FIGO I + II 1.466 0.648 0.866 0.487 1.933 0.047
FIGO III + IV 1.558 0.971 2.271