Table 3.

Effects of cumulative vascular risk factor score and race on amnestic and non-amnestic MCI odds

Cognitive Status	Predictor	Block 1		Block 2		Block 3		Block 4
naMCI		OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI
	Age	0.982	0.955–1.009	0.989	0.962–1.016	0.991	0.964–1.019	0.991	0.964–1.018
	Education	0.942	0.888–0.999	1.073 *	1.003–1.148	1.078 *	1.008–1.153	1.078 *	1.008–1.154
	Sex/gender (women)	1.452	0.974–2.164	1.580 *	1.055–2.366	1.566 *	1.045–2.347	1.565 *	1.044–2.347
	Race (Black)	1.178	0.844–1.645	0.644 **	0.442–0.937	0.620 *	0.425–0.906	0.287 **	0.134–0.614
	Vocabulary	-	-	0.829 ***	0.792–0.869	0.829 ***	0.792–0.869	0.828 ***	0.790–0.867
	VRF	-	-	-	-	1.111	0.959–1.287	0.986	0.825–1.177
	Race × VRF	-	-	-	-	-	-	1.473 **	1.072–2.025
aMCI		OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI
	Age	1.050 ***	1.03–1.07	1.058 ***	1.037–1.079	1.060 ***	1.039–1.082	1.060 ***	1.039–1.082
	Education	0.923 ***	0.882–0.965	1.074 ***	1.019–1.132	1.078 **	1.023–1.136	1.077 **	1.022–1.136
	Sex/gender (women)	0.956	0.724–1.261	1.074	0.807–1.430	1.062	0.797–1.415	1.062	0.797–1.415
	Race (Black)	1.368 *	1.026–1.333	0.700 *	0.520–0.941	0.679 *	0.504–0.916	0.652	0.373–1.138
	Vocabulary	-	-	0.811 ***	0.782–0.841	0.811 ***	0.782–0.841	0.811 ***	0.782–0.841
	VRF	-	-	-	-	1.095	0.974–1.232	1.090	0.947–1.254
	Race × VRF	-	-	-	-	-	-	1.024	0.794–1.319

Data represents conditional odds ratios (OR=exp[β]) from stepwise multinomial logistic regression models. naMCI=non-amnestic MCI; aMCI=amnestic MCI; CI=confidence interval (lower bound – upper bound); VRF=cumulative vascular risk factor score. Cognitively normal participants are reference.

^***p< .001;

^**p< .01;

^*p< .05 and are bolded.