Table 4.
Cognitive Status | Predictor | Diabetes | Hypertension | High Cholesterol | Obesity | Current Smoking | |||||
---|---|---|---|---|---|---|---|---|---|---|---|
naMCI | OR | 95% CI | OR | 95% CI | OR | 95% CI | OR | 95% CI | OR | 95% CI | |
Age | 0.990 | 0.963–1.018 | 0.987 | 0.960–1.014 | 0.987 | 0.960–1.014 | 0.990 | 0.962–1.018 | 0.987 | 0.959–1.015 | |
Education | 1.077 * | 1.007–1.152 | 1.077 * | 1.007–1.152 | 1.074 * | 1.003–1.149 | 1.077 * | 1.006–1.153 | 1.070 | 0.999–1.146 | |
Sex/gender (women) | 1.587 * | 1.059–2.378 | 1.592 * | 1.062–2.388 | 1.609 * | 1.073–2.414 | 1.561 * | 1.034–2.358 | 1.565 * | 1.038–2.359 | |
Vocabulary | 0.829 *** | 0.791–0.868 | 0.830 *** | 0.792–0.869 | 0.827 *** | 0.790–0.867 | 0.826 *** | 0.788–0.866 | 0.827 *** | 0.789–0.867 | |
Race (Black) | 0.616 * | 0.406–0.934 | 0.495 | 0.229–1.070 | 0.455 ** | 0.275–0.752 | 0.494 ** | 0.301–0.813 | 0.414–0.918 | ||
Individual VRF | 1.428 | 0.827–2.465 | 1.581 * | 1.071–2.334 | 0.698 | 0.481–1.014 | 0.789 | 0.517–1.203 | 0.670 | 0.264–1.700 | |
Race (Black) × Individual vRf | 1.011 | 0.437–2.340 | 1.271 | 0.548–2.948 | 2.061 * | 1.054–4.030 | 2.024 * | 1.007–4.067 | 1.737 | 0.508–5.943 | |
aMCI | OR | 95% CI | OR | 95% CI | OR | 95% CI | OR | 95% CI | OR | 95% CI | |
Age | 1.061 *** | 1.040–1.082 | 1.058 *** | 1.037–1.079 | 1.058 *** | 1.037–1.079 | 1.057 *** | 1.035–1.079 | 1.058 *** | 1.037–1.079 | |
Education | 1.080 ** | 1.024–1.138 | 1.076 ** | 1.021–1.134 | 1.075 ** | 1.020–1.133 | 1.068 * | 1.012–1.127 | 1.081 ** | 1.025–1.140 | |
Sex/gender (women) | 1.081 | 0.810–1.442 | 1.065 | 0.800–1.419 | 1.067 | 0.800–1.423 | 1.076 | 0.801–1.444 | 1.058 | 0.794- | |
Vocabulary | 0.809 *** | 0.779–0.839 | 0.810 *** | 0.780–0.840 | 0.811 *** | 0.782–0.841 | 0.813 *** | 0.783–0.844 | 0.806 *** | 0.777–0.837 | |
Race (Black) | 0.654 * | 0.468–0.914 | 0.701 | 0.422–1.165 | 0.793 | 0.546–1.154 | 0.711 | 0.492–1.026 | 0.669 * | 0.489–0.915 | |
Individual VRF | 2.059 *** | 1.383–3.065 | 1.086 | 0.810–1.455 | 0.987 | 0.739–1.318 | 1.030 | 0.744–1.425 | 1.023 | 0.528–1.984 | |
Race (Black) × Individual vRf | 0.916 | 0.484–1.734 | 0.989 | 0.552–1.770 | 0.760 | 0.444–1.303 | 1.048 | 0.604–1.819 | 1.314 | 0.528–3.270 |
Data represents conditional odds ratios (OR=exp[β]) from multinomial logistic regression models predicting MCI status by race. naMCI=non-amnestic MCI; aMCI=amnestic MCI; CI=confidence interval; Individual VRF=individual vascular risk factor associated with heading. Cognitively normal participants are reference.
p< .001;
p< .01;
p< .05 and are bolded.