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. 2021 Jul 12;8:688897. doi: 10.3389/fnut.2021.688897

Table 4.

Odds ratios (ORs) and 95% confidence intervals (CIs) for the association of yearly solanaceous vegetables intake and colorectal cancer risk according to subsite.

Yearly solanaceous vegetables intake quartiles Proximal colon cancer (n = 396) Distal colon cancer (n = 418) Rectal cancer (n = 852)
Cases/ controls (n) OR (95%CI) Adjusted ORa (95%CI) Cases/ controls (n) OR (95%CI) Adjusted OR (95%CI) Cases/ controls (n) OR (95%CI) Adjusted OR (95%CI)
Potato
Q1 37/48 1.00 1.00 46/46 1.00 1.00 81/102 1.00 1.00
Q2 52/57 1.16 (0.67,2.01) 1.58 (0.75,3.35) 60/55 1.06 (0.62,1.83) 0.87 (0.38,1.96) 105/99 1.34 (0.90,2.00) 1.28 (0.74,2.23)
Q3 12/12 1.23 (0.52,2.88) 2.80 (0.81,9.75) 9/14 0.63 (0.24,1.66) 0.66 (0.16,2.71) 32/26 1.58 (0.86,2.92) 1.81 (0.80,4.08)
Q4 97/81 1.51 (0.91,2.50) 3.22 (1.54,6.71) 94/94 0.98 (0.58,1.68) 1.81 (0.82,4.00) 208/199 1.31 (0.93,1.87) 1.36 (0.85,2.19)
P for Trendb 0.412 0.013 0.733 0.119 0.330 0.454
Eggplant
Q1 74/47 1.00 1.00 65/65 1.00 1.00 163/85 1.00 1.00
Q2 48/34 0.90 (0.48,1.67) 0.83 (0.37,1.85) 45/59 0.54 (0.32,0.93) 0.60 (0.27,1.35) 99/96 0.59 (0.41,0.85) 0.55 (0.34,0.90)
Q3 46/44 0.59 (0.32,1.09) 0.66 (0.31,1.41) 53/50 0.73 (0.41,1.28) 1.10 (0.49,2.44) 94/114 0.39 (0.26,0.59) 0.57 (0.34,0.98)
Q4 30/73 0.20 (0.10,0.39) 0.25 (0.10,0.65) 46/55 0.57 (0.32,1.03) 1.06 (0.47,2.40) 70/131 0.24 (0.16,0.37) 0.32 (0.18,0.56)
P for Trend <0.001 0.03 0.111 0.441 <0.001 0.001
Sweet Pepper
Q1 55/39 1.00 1.00 66/43 1.00 1.00 124/90 1.00 1.00
Q2 52/46 0.86 (0.48,1.55) 0.65 (0.29,1.46) 45/51 0.54 (0.29,1.99) 0.39 (0.16,0.97) 108/117 0.66 (0.44,0.97) 0.47 (0.27,0.82)
Q3 41/57 0.53 (0.30,0.93) 0.41 (0.19,0.93) 43/46 0.57 (0.31,1.04) 0.52 (0.21,1.25) 92/105 0.64 (0.43,0.94) 0.50 (0.29,0.87)
Q4 50/56 0.64 (0.36,1.14) 0.48 (0.21,1.09) 55/69 0.48 (0.27,0.84) 0.39 (0.17,0.89) 102/114 0.62 (0.41,0.95) 0.47 (0.26,0.85)
P for Trend 0.125 0.146 0.062 0.114 0.059 0.019
Tomato
Q1 57/51 1.00 1.00 69/45 1.00 1.00 134/92 1.00 1.00
Q2 46/38 1.10 (0.62,1.95) 0.89 (0.40,2.01) 43/53 0.56 (0.33,0.95) 0.69 (0.34,1.38) 108/103 0.70 (0.47,1.03) 0.73 (0.43,1.24)
Q3 56/41 1.22 (0.69,2.16) 1.68 (0.74,3.81) 62/62 0.62 (0.37,1.04) 0.71 (0.35,1.42) 101/112 0.60 (0.40,0.90) 0.60 (0.35,1.03)
Q4 39/68 0.42 (0.23,0.78) 0.57 (0.22,1.48) 35/49 0.39 (0.20,0.77) 0.85 (0.33,2.16) 83/119 0.45 (0.30,0.68) 0.57 (0.33,1.01)
P for Trend 0.006 0.098 0.032 0.680 0.002 0.183
Total solanaceous vegetables
Q1 62/52 1.00 1.00 68/54 1.00 1.00 123/102 1.00 1.00
Q2 51/48 0.93 (0.55,1.59) 1.83 (0.85,3.93) 57/50 0.93 (0.55,1.57) 0.81 (0.39,1.71) 121/110 0.92 (0.64,1.33) 0.82 (0.49,1.39)
Q3 46/40 0.92 (0.52,1.61) 1.68 (0.76,3.72) 46/54 0.65 (0.38,1.11) 1.20 (0.56,2.59) 93/114 0.65 (0.44,0.96) 0.69 (0.39,1.21)
Q4 39/58 0.49 (0.26,0.90) 1.52 (0.59,3.89) 38/51 0.52 (0.29,0.96) 1.22 (0.53,2.82) 89/100 0.70 (0.46,1.06) 0.91 (0.51,1.63)
P for Trend 0.111 0.414 0.143 0.785 0.117 0.590
a

Adjusted by BMI, colon cancer in first-degree relative, smoking status, alcohol drinking, eating breakfast, and fried food, grilled food, and hot and spicy food intake as category variables; and total energy, total fruits, milk product, and red meat intake as continuous variables.

b

Test for trends calculated with the median intake of each category of solanaceous vegetable intake as a continuous variable.

Bold values indicates statistical significance, which is defined as a two-side P < 0.05.