Table 3.

Univariate and multivariate Cox regression analyses of the risk factors for 30% eGFR decline from baseline.

Variables	Unadjusted	p-value	Adjusted	p-value
	HR (95%CI)		HR (95%CI)
TNFR2 (T3 vs. T1 + T2)	5.68 (2.50, 12.89)	<0.001	4.76 (1.79, 12.64)	0.002
Age (per 1 increase)	1.00 (0.97, 1.03)	0.908	1.00 (0.96, 1.03)	0.812
Male	1.21 (0.49, 3.00)	0.677	2.09 (0.77, 5.67)	0.150
Systolic BP (per 1 increase)	1.00(0.98, 1.03)	0.901	0.99 (0.96, 1.02)	0.388
Presence of diabetes	1.06 (0.48, 2.33)	0.892	0.85 (0.37, 1.95)	0.701
Treatment (Febuxostat vs. Placebo)	1.22 (0.59, 2.53)	0.601	1.35 (0.65, 2.84)	0.422
Uric acid (per 1 increase)	0.93 (0.62, 1.42)	0.746	0.76 (0.50, 1.14)	0.180
log_hsCRP (per 1 increase)	1.25 (0.95, 1.63)	0.108	1.18 (0.90, 1.55)	0.226
eGFR (per 1 increase)	0.96 (0.92, 1.00)	0.072	0.99 (0.95, 1.04)	0.789
log_ACR (per 1 increase)	1.42 (1.14, 1.78)	0.002	1.31 (1.02, 1.69)	0.034

Abbreviations used in this table are the same as in Table 1.

log_, log-transformed.