Table 3.
Clinical input data for effectiveness.
| Effectiveness parameters | Value (TB case detected per 1,000 screening) | Range¶ | Distributions§ | Alpha | Beta |
|---|---|---|---|---|---|
| COAD patients | |||||
| Symptomatic | 20.4 | 15.3–25.5 | Beta | 15.65 | 751.66 |
| Asymptomatic | 1.8 | 1.4–2.3 | Beta | 12.93 | 7173.11 |
| CCRC inmates | |||||
| Symptomatic | 0.0 | na | na | na | na |
| Asymptomatic | 3.3 | 2.5–4.1 | Beta | 16.96 | 5121.28 |
| Diabetes mellitus patients | |||||
| Symptomatic | 23.4 | 17.6–29.3 | Beta | 15.34 | 640.15 |
| Asymptomatic | 1.5 | 1.1–1.9 | Beta | 14.04 | 9345.90 |
| ESRF (haemodialysis) | |||||
| Symptomatic | 75.3 | 56.5–94.1 | Beta | 14.76 | 181.2470 |
| Asymptomatic | 1.0 | 0.8–1.3 | Beta | 11.10 | 11087.90 |
| Smokers | |||||
| Symptomatic | 37.6 | 28.2–47.0 | Beta | 15.36 | 393.17 |
| Asymptomatic | 2.4 | 1.8–3.0 | Beta | 15.96 | 6633.71 |
| PL HIV | |||||
| Symptomatic | 57.5 | 43.1–71.9 | Beta | 15.18 | 248.84 |
| Asymptomatic | 6.1 | 4.6–7.6 | Beta | 16.43 | 2677.14 |
| Methadone clinic clients | |||||
| Symptomatic | 0.0 | na | na | na | na |
| Asymptomatic | 0.0 | na | na | na | na |
| Prisoners | |||||
| Symptomatic | 97.3 | 73.0–121.6 | Beta | 14.38 | 133.37 |
| Asymptomatic | 8.4 | 6.3–10.5 | Beta | 15.86 | 1871.90 |
| Elderly nursing home residents | |||||
| Symptomatic | 0.0 | na | na | na | na |
| Asymptomatic | 0.0 | na | na | na | na |
| Rheumatoid arthritis patients | |||||
| Symptomatic | 0.0 | na | na | na | na |
| Asymptomatic | 0.0 | na | na | na | na |
| Elderly (60 years and above) | |||||
| Symptomatic | 46.9 | 35.2–58.6 | Beta | 15.27 | 310.27 |
| Asymptomatic | 3.5 | 2.6–4.4 | Beta | 15.07 | 4289.80 |
¶
The effectiveness parameter values are varied by ±25%.
§
Selection of distributions for each parameter are believed to be the best practice. Beta distribution is best used for effectiveness since this value also represents probability.