FIGURE 5.

Gene expression of interleukin (IL)-10, IL-20 and IL-24 in bronchial biopsies from patients with asthma of different severity categories. The data are from U-BIOPRED Project and Australian Newcastle severe asthma cohorts (GSE147881). a) IL-10 gene expression was significantly decreased in the lungs of patients with severe asthma compared to healthy controls. b) There was a trend towards increased lung IL-20 expression in patients with mild/moderate asthma compared to healthy controls. c) IL-24 gene expression was significantly decreased in the lungs of patients with mild/moderate asthma compared to healthy controls. Two-way comparison was done using two-tailed t-tests. ns: nonsignificant. *: p<0.05; **: p<0.01.