Table 1.
Clinical and laboratory characteristics of COVID-19 in early infancy.
| Asymptomatic | Mild | Moderate | Severe/Critical | |
|---|---|---|---|---|
| N | 2 | 25 | 5 | 4 |
| Age at presentation, days; mean (range) | 38 (15–61) | 50 (1–90) | 18 (1–90) | 21.5 (1–90) |
| Male, n (%) | 1 (50) | 12 (48) | 5 (100) | 2 (50) |
| Spontaneous vaginal delivery, n (%) | 2 (100) | 16 (64) | 5 (100) | 4 (100) |
| Mother age, years; mean (range) | 25 (22–29) | 31 (20–43) | 27.5 (22–41) | 34 |
| Gestational age, weeks; mean (range) | 39 (39–41) | 38 (23–40) | 38 (38–39) | 37 (37–37) |
| Birthweight, g; mean (range) | 3,395 (2,530–3,600) | 3,144 (2,530–3,800) | 2,815 (2,800–3,670) | 3,550 (2,500–4,600) |
| Mother's COVID-19 status at presentation, positive, n (%) | 2 | 12 | 2 | 1 |
| Breastfeeding, n | 2 | 14 | 3 | 2 |
| Fever, n (%) | NA | 18 | 4 | 3 |
| Respiratory signs, n | NA | 15 | 5 | 3 |
| Gastrointestinal signs, n | NA | 7 | 2 | 1 |
| Number hospitalized | 2 | 15 | 5 | 4 |
| White blood cells; mean (range) | 14 (10.9–17.9) | 7.3 (2.8–12.6) | 10.5 (6.9–12.5) | 10.15 (6–29.4) |
| Platelet counts; mean (range) | 259 (177–341) | 327 (144–614) | 380 (263–552) | 231 (43–360) |
| Platelet <150 | 0 | 1 | 0 | 0 |
| Platelet <100 | 0 | 0 | 0 | 1 |
| Abnormal CXR | NA | 14 (56) | 5 (100) | 4 (100) |
| Resource utilization and outcome | ||||
| O2 therapy, days; mean (range) | 0 | 0 | 0 | 15 (14–75) |
| Length of stay in intensive care unit, days; mean (range) | 0 | 0 | 0 | 12.5 (3–16) |
| Hospital length of stay, days; mean (range) | 6 (5–8) | 4 (2–10) | 4 (2–7) | 70 (15–75) |
| Mortality | 0 | 0 | 0 | 1 (25%) |